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The Golden Age of Vaccine Development
Microbiology had its golden age in the late nineteenth century, when researchers identified the bacterial causes of tuberculosis, cholera, typhoid, and a dozen other diseases in rapid succession. Antibiotics had theirs in the mid-twentieth century. Both booms eventually slowed. Vaccine development, by contrast, appears to be speeding up -- and the most productive era may still lie ahead, Works in Progress writes in a story.
In the first half of the 2020s alone, researchers delivered the first effective vaccines against four different diseases: Covid-19, malaria, RSV and chikungunya. No previous decade matched that output. The acceleration rests on infrastructure that took two centuries to assemble. Edward Jenner's 1796 smallpox vaccine was a lucky accident he didn't understand. Louis Pasteur needed ninety years to turn that luck into systematic methods -- attenuation and inactivation -- that could be applied to other diseases. Generations of scientists then built the supporting machinery: Petri dishes for bacterial culture, techniques to keep animal cells alive outside the body, bioreactors for industrial production, sterilization and cold-chain logistics.
Those tools have now compounded. Cryo-electron microscopy reveals viral proteins atom by atom, a capability that directly enabled the RSV vaccine after earlier attempts failed. Genome sequencing costs collapsed from roughly $100 million per human genome in 2001 to under $1,000 by 2014, according to data from the National Human Genome Research Institute. The mRNA platform, refined through work by Katalin Kariko, Drew Weissman, and others, allows vaccines to be redesigned in weeks rather than years. The trajectory suggests more breakthroughs are possible. Whether they arrive depends on continued investment, however.
Read more of this story at Slashdot.
3 safe ways to install Linux apps that aren’t in your repo (without breaking anything) - How-To Geek
Categories: Linux
America Is Falling Out of Love With Pizza
The restaurant industry is trying to figure out whether America has hit peak pizza. From a report: Once the second-most common U.S. restaurant type, pizzerias are now outnumbered by coffee shops and Mexican food eateries, according to industry data. Sales growth at pizza restaurants has lagged behind the broader fast-food market for years, and the outlook ahead isn't much brighter.
"Pizza is disrupted right now," Ravi Thanawala, chief financial officer and North America president at Papa John's International, said in an interview. "That's what the consumer tells us." The parent of the Pieology Pizzeria chain filed for chapter 11 bankruptcy protection in December. Others, including the parent of Anthony's Coal Fired Pizza & Wings and Bertucci's Brick Oven Pizza & Pasta, earlier filed for bankruptcy.
Pizza once was a novelty outside big U.S. cities, providing room for growth for independent shops and then chains such as Pizza Hut with its red roof dine-in restaurants. Purpose-made cardboard boxes and fleets of delivery drivers helped make pizza a takeout staple for those seeking low-stress meals. Today, pizza shops are engaged in price wars with one another and other kinds of fast food. Food-delivery apps have put a wider range of cuisines and options at Americans' fingertips. And $20 a pie for a family can feel expensive compared with $5 fast-food deals, frozen pizzas or eating a home-cooked meal.
[...] Pizza's dominance in American restaurant fare is declining, however. Among different cuisines, it ranked sixth in terms of U.S. sales in 2024 among restaurant chains, down from second place during the 1990s, Technomic said. The number of pizza restaurants in the U.S. hit a record high in 2019 and has declined since then, figures from the market-research firm Datassential show. Further reading, at WSJ: The Feds Need to Bail Out the Pizza Industry.
Read more of this story at Slashdot.
Steam games finally run better on Linux Arm devices, and you can test them right now - XDA
Categories: Linux
Amazon's New Manager Dashboard Flags 'Low-Time Badgers' and 'Zero Badgers'
Amazon has begun equipping managers with a dashboard that tracks not just whether corporate employees show up to the office but how long they stay once they're there, according to an internal document obtained by Business Insider. The system, which started rolling out in December, flags "Low-Time Badgers" who average less than four hours daily over an eight-week period and "Zero Badgers" who don't badge into any building during that span.
Read more of this story at Slashdot.
Torvalds Tells Kernel Devs To Stop Debating AI Slop - Bad Actors Won't Follow the Rules Anyway
Linus Torvalds has weighed in on an ongoing debate within the Linux kernel development community about whether documentation should explicitly address AI-generated code contributions, and his position is characteristically blunt: stop making it an issue. The Linux creator was responding to Oracle-affiliated kernel developer Lorenzo Stoakes, who had argued that treating LLMs as "just another tool" ignores the threat they pose to kernel quality. "Thinking LLMs are 'just another tool' is to say effectively that the kernel is immune from this," Stoakes wrote.
Torvalds disagreed sharply. "There is zero point in talking about AI slop," he wrote. "Because the AI slop people aren't going to document their patches as such." He called such discussions "pointless posturing" and said that kernel documentation is "for good actors." The exchange comes as a team led by Intel's Dave Hansen works on guidelines for tool-generated contributions. Stoakes had pushed for language letting maintainers reject suspected AI slop outright, arguing the current draft "tries very hard to say 'NOP.'" Torvalds made clear he doesn't want kernel documentation to become a political statement on AI. "I strongly want this to be that 'just a tool' statement," he wrote.
Read more of this story at Slashdot.
Torvalds Tells Kernel Devs To Stop Debating AI Slop - Bad Actors Won't Follow the Rules Anyway
Linus Torvalds has weighed in on an ongoing debate within the Linux kernel development community about whether documentation should explicitly address AI-generated code contributions, and his position is characteristically blunt: stop making it an issue. The Linux creator was responding to Oracle-affiliated kernel developer Lorenzo Stoakes, who had argued that treating LLMs as "just another tool" ignores the threat they pose to kernel quality. "Thinking LLMs are 'just another tool' is to say effectively that the kernel is immune from this," Stoakes wrote.
Torvalds disagreed sharply. "There is zero point in talking about AI slop," he wrote. "Because the AI slop people aren't going to document their patches as such." He called such discussions "pointless posturing" and said that kernel documentation is "for good actors." The exchange comes as a team led by Intel's Dave Hansen works on guidelines for tool-generated contributions. Stoakes had pushed for language letting maintainers reject suspected AI slop outright, arguing the current draft "tries very hard to say 'NOP.'" Torvalds made clear he doesn't want kernel documentation to become a political statement on AI. "I strongly want this to be that 'just a tool' statement," he wrote.
Read more of this story at Slashdot.
Categories: Linux
Craigslist at 30: No Algorithms, No Ads, No Problem
Craigslist, the 30-year-old classifieds site that looks virtually unchanged since the dial-up era, continues to draw more than 105 million monthly users and remains enormously profitable despite never spending a cent on advertising or marketing. The site ranks as the 40th most popular website in the United States, according to Internet data company Similarweb.
University of Pennsylvania associate professor Jessa Lingel called it the "ungentrified" Internet. Unlike Facebook Marketplace, Etsy, or DePop, Craigslist doesn't use algorithms to track users or predict what they want to see. There are no public profiles, no rating systems, no likes or shares. The site effectively disincentivizes the clout-chasing and virality-seeking that dominates platforms like TikTok and Instagram.
Craigslist began in 1995 as an email list for a few hundred San Francisco Bay Area locals sharing events and job openings. Engineer Craig Newmark even recruited CEO Jim Buckmaster through a site ad. The two spent roughly a decade battling eBay in court after the tech giant purchased a minority stake in 2004, ultimately buying back shares and regaining full control in 2015.
Read more of this story at Slashdot.
iOS 26 Shows Unusually Slow Adoption Months After Release
Apple's iOS 26 appears to be witnessing the slowest adoption rate in recent memory, with third-party analytics from StatCounter indicating that only 15 to 16% of active iPhones worldwide are running the operating system nearly four months after its September release. The figures stand in stark contrast to iOS 18, which had reached approximately 63% adoption by January 2025, and iOS 17, which hit 54% by January 2024. iOS 16 had surpassed 60% by January 2023.
StatCounter's breakdown for January 2026 shows iOS 26.1 accounting for roughly 10.6% of devices, iOS 26.2 at about 4.6%, and the original iOS 26.0 at 1.1%. More than 60% of iPhones tracked by the analytics firm remain on iOS 18.
MacRumors' own visitor data tells a similar story: 89.3% of the site's readers were on iOS 18 during the first week of January 2025, but only 25.7% are running iOS 26 during the same period this year. iOS 26 introduced Liquid Glass, a sweeping visual redesign that replaces much of the traditional opaque interface with translucent layers, blurred backgrounds, and dynamic depth effects.
Read more of this story at Slashdot.
Amazon Wants To Know What Every Corporate Employee Accomplished Last Year
Amazon is now requiring its corporate employees to submit a list of three to five accomplishments that represent their best work as part of an overhauled performance review process, according to Business Insider, which cites internal documents.
The company's internal Forte review system previously asked employees softer questions like "When you're at your best, how do you contribute?" but the new standards place greater emphasis on individual productivity and specific deliverables. Amazon's roughly 350,000 corporate employees must also outline actions they plan to take to continue growing at the company.
Read more of this story at Slashdot.
Linux Kernel Bugs Can Hide for 20 Years - Bitdefender
Linux Kernel Bugs Can Hide for 20 Years Bitdefender
Categories: Linux
Send To Kindle from Microsoft Word is Discontinued
Microsoft is discontinuing its Send to Kindle integration in Word, ending a feature that allowed Microsoft 365 subscribers to send documents directly to their Kindle e-readers and preserve complex formatting through fixed layouts.
The company updated its documentation to announce that beginning February 9th, 2026, the Send to Kindle feature will no longer work across Web, Win32, and Mac platforms. Microsoft has not disclosed why it's killing the integration but recommends users switch to Amazon's official Send to Kindle app. The feature launched in 2023 and was particularly valued by Kindle Scribe owners who could annotate the transferred documents.
Read more of this story at Slashdot.
