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Google DeepMind's chief business officer says Alphabet's drug-discovery company Isomorphic Labs "is preparing to launch human trials of AI-designed drugs," according to a report in Fortune, "pairing cutting-edge AI with pharma veterans to design medicines faster, cheaper, and more accurately." "There are people sitting in our office in King's Cross, London, working, and collaborating with AI to design drugs for cancer," said Colin Murdoch [DeepMind's chief business officer and president of Isomorphic Labs]. "That's happening right now." After years in development, Murdoch says human clinical trials for Isomorphic's AI-assisted drugs are finally in sight. "The next big milestone is actually going out to clinical trials, starting to put these things into human beings," he said. "We're staffing up now. We're getting very close." The company, which was spun out of DeepMind in 2021, was born from one of DeepMind's most celebrated breakthroughs, AlphaFold, an AI system capable of predicting protein structures with a high level of accuracy. Interactions of AlphaFold progressed from being able to accurately predict individual protein structures to modeling how proteins interact with other molecules like DNA and drugs. These leaps made it far more useful for drug discovery, helping researchers design medicines faster and more precisely, turning the tool into a launchpad for a much larger ambition... In 2024, the same year it released AlphaFold 3, Isomorphic signed major research collaborations with pharma companies Novartis and Eli Lilly. A year later, in April 2025, Isomorphic Labs raised $600 million in its first-ever external funding round, led by Thrive Capital. The deals are part of Isomorphic's plan to build a "world-class drug design engine..." Today, pharma companies often spend millions attempting to bring a single drug to market, sometimes with just a 10% chance of success once trials begin. Murdoch believes Isomorphic's tech could radically improve those odds. "We're trying to do all these things: speed them up, reduce the cost, but also really improve the chance that we can be successful," he says. He wants to harness AlphaFold's technology to get to a point where researchers have 100% conviction that the drugs they are developing are going to work in human trials. "One day we hope to be able to say — well, here's a disease, and then click a button and out pops the design for a drug to address that disease," Murdoch said. "All powered by these amazing AI tools."

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PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

PoC Released for Linux Privilege Escalation Vulnerability via udisksd and libblockdev  CyberSecurityNews

"The China Film Foundation, a nonprofit fund under the Chinese government, plans to use AI to revitalize 100 kung fu classics including Police Story, Once Upon a Time in China and Fist of Fury, featuring Jackie Chan, Jet Li and Bruce Lee, respectively," reports the Los Angeles Times. "The foundation said it will partner with businesses including Shanghai Canxing Culture & Media Co., which will license 100 Hong Kong films to AI companies to reintroduce those movies to younger audiences globally." The foundation said there are opportunities to use AI to tell those stories through animation, for example. There are plans to release an animated version of director John Woo's 1986 film A Better Tomorrow that uses AI to "reinterpret" Woo's "signature visual language," according to an English transcript of the announcement.... The project raised eyebrows among U.S. artists, many of whom are deeply wary of the use of AI in creative pursuits. The Directors Guild of America said AI is a creative tool that should only be used to enhance the creative storytelling process and "it should never be used retroactively to distort or destroy a filmmaker's artistic work... The DGA strongly opposes the use of AI or any other technology to mutilate a film or to alter a director's vision," the DGA said in a statement. "The Guild has a longstanding history of opposing such alterations on issues like colorization or sanitization of films to eliminate so-called 'objectionable content', or other changes that fundamentally alter a film's original style, meaning, and substance." The project highlights widely divergent views on AI's potential to reshape entertainment as the two countries compete for dominance in the highly competitive AI space.... During the project's announcement, supporters touted the opportunity AI will bring to China to further its cultural message globally and generate new work for creatives. At the same time, they touted AI's disruption of the filmmaking process, saying the A Better Tomorrow remake was completed with just 30 people, significantly fewer than a typical animated project. China is a "more brutal society in that sense," said Eric Harwit, professor of Asian studies at the University of Hawaii at Manoa. "If somebody loses their job because artificial intelligence is taking over, well, that's just the cost of China's moving forward.... You don't have those freestanding labor organizations, so they don't have that kind of clout to protest against the Chinese using artificial intelligence in a way that might reduce their job opportunities or lead to layoffs in the sector..." The kung fu revitalization efforts will extend into other areas, including the creation of a martial arts video game. The article also includes an interesting statistic. "Many people in China embrace AI, with 83% feeling confident that AI systems are designed to act in the best interest of society, much higher than the U.S. where it's 37%, according to a survey from the United Nations Development Program."

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"A growing group of young, college-educated Americans are struggling to find work," reports the Minnesota Star Tribune, "as the unemployment rate for recent graduates outpaces overall unemployment for the first time in decades." While the national unemployment rate has hovered around 4% for months, the rate for 20-something degree holders is nearly 6%, data from the Federal Reserve Bank of New York shows. [And for young workers (ages 22 to 27) without a degree it's 6.9%.] The amount of time young workers report being unemployed is also on the rise. Economists attribute some of the shift to normal post-pandemic cooling of labor market, which is making it harder for job-seekers of all ages to land a gig. But there's also widespread economic uncertainty causing employers to pull back on hiring and signs AI could replace entry-level positions.... Business schools nationwide were among the first to see the labor market shift in early 2023 as tech industry cuts bled into other sectors, said Maggie Tomas, Business Career Center executive director at Carlson. Tariffs and stock market volatility have only added to the uncertainty, she said. In 2022, when workers had their pick of jobs, 98% of full-time Carlson MBA graduates had a job offer in a field related to their degree within three months of graduation, according to the school. That number, which Tomas said is usually 90% or higher, dropped to 89% in 2023 and 83% in 2024. Part of the challenge, she said, is recent graduates are now competing with more experienced workers who are re-entering the market amid layoffs and hiring freezes... After doing a lot of hiring in 2021 and 2022, Securian Financial in St. Paul is prioritizing internal hires, said Human Resources Director Leah Henrikson. Many entry-level roles have gone to current employees looking for a change, she said. "We are still looking externally, it's just the folks that we are looking for externally tend ... to fulfill a specific skill gap we may have at that moment in time," Henrikson said.

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The DistroWatch news feed is brought to you by TUXEDO COMPUTERS. This week in DistroWatch Weekly:
Review: GLF OS Omnislash Beta
News: Alpine seeks to reduce maintenance burden for X11 desktops, Fedora drops proposal for removing 32-bit packages, AlmaLinux extends EPEL support for more CPUs, Ubuntu dropping older RISC-V processors, Rhino Linux working with UBports, PCLinuxOS experiences website outage
Questions and....

Investigators of a deadly Boeing 787 crash "are studying possible dual engine failure as a scenario that prevented the Boeing Co. 787 jet from staying airborne," reports Bloomberg: Pilots from the airline reenacted the doomed aircraft's parameters in a flight simulator, including with the landing gear deployed and the wing flaps retracted, and found those settings alone didn't cause a crash, according to people familiar with the investigation. [Also, analysis of the wreckage "suggests the wing flaps and slats, which help an aircraft increase lift during takeoff, were extended correctly."] The result, alongside the previous discovery that an emergency-power turbine deployed seconds before impact, has reinforced the focus on a technical failure as one possible cause, said the people, who asked not to be identified discussing nonpublic deliberations... [The turbine deploys "in the case of electrical failure," the article points out, and "was activated before the plane crashed, according to previous findings. That fan helps provide the aircraft with vital power, though it's far too small to generate any lift."] Pilots who reviewed the footage have pointed to the fact that the landing gear was already partially tilted forward, suggesting the cockpit crew had initiated the retraction sequence of the wheels. At the same time, the landing-gear doors had not opened, which pilots say might mean that the aircraft experienced a loss of power or a hydraulic failure — again pointing to possible issues with the engines that provide the aircraft's electricity.

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"California residents who lit illegal fireworks over the July 4 holiday may be in for a nasty surprise in the mail thanks to covert fire department operations," reports SFGate. "A number of California cities, including Sacramento, have begun using drones to locate people shooting off illegal fireworks." From Wednesday to Saturday night, the Sacramento Fire Department's special fireworks task force patrolled the streets with unmarked cars and drones, focusing on neighborhoods where they've had prior complaints. Task force officers and the drones took photos of the illegal activity, and within 30 days the property owner where the fireworks were used could receive a fine in the mail... This year, Sacramento upped the fine to $1,000 for the first firework, $2,500 for the second and $5,000 per firework after that. If you lit a firework on city property, such as a park or a school, the fine goes up to $10,000 each. There's no limit to how many fines you can be issued... This year, a number of cities across the state announced they would be using drones to find scofflaws, among them Indio, Riverside, Hemet, Brea and towns in Tulare County... Fox40 reported on Saturday that around 60 citations were being prepared in Sacramento, with more likely on the way as fire officials review surveillance footage. Last year for illegal fireworks, one Sacramento-area resident received a $100,000 fine.

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Linux 6.16-rc5 Released With A Performance Fix, Bcachefs Fixes & New Device Support  Phoronix

China "is pouring money into building an AI supply chain with as little reliance on the U.S. as possible," reports the Wall Street Journal. And now Chinese AI companies "are loosening the U.S.'s global stranglehold on AI," reports the Wall Street Journal, "challenging American superiority and setting the stage for a global arms race in the technology." In Europe, the Middle East, Africa and Asia, users ranging from multinational banks to public universities are turning to large language models from Chinese companies such as startup DeepSeek and e-commerce giant Alibaba as alternatives to American offerings such as ChatGPT... Saudi Aramco, the world's largest oil company, recently installed DeepSeek in its main data center. Even major American cloud service providers such as Amazon Web Services, Microsoft and Google offer DeepSeek to customers, despite the White House banning use of the company's app on some government devices over data-security concerns. OpenAI's ChatGPT remains the world's predominant AI consumer chatbot, with 910 million global downloads compared with DeepSeek's 125 million, figures from researcher Sensor Tower show. American AI is widely seen as the industry's gold standard, thanks to advantages in computing semiconductors, cutting-edge research and access to financial capital. But as in many other industries, Chinese companies have started to snatch customers by offering performance that is nearly as good at vastly lower prices. A study of global competitiveness in critical technologies released in early June by researchers at Harvard University found China has advantages in two key building blocks of AI, data and human capital, that are helping it keep pace... Leading Chinese AI companies — which include Tencent and Baidu — further benefit from releasing their AI models open-source, meaning users are free to tweak them for their own purposes. That encourages developers and companies globally to adopt them. Analysts say it could also pressure U.S. rivals such as OpenAI and Anthropic to justify keeping their models private and the premiums they charge for their service... On Latenode, a Cyprus-based platform that helps global businesses build custom AI tools for tasks including creating social-media and marketing content, as many as one in five users globally now opt for DeepSeek's model, according to co-founder Oleg Zankov. "DeepSeek is overall the same quality but 17 times cheaper," Zankov said, which makes it particularly appealing for clients in places such as Chile and Brazil, where money and computing power aren't as plentiful... The less dominant American AI companies are, the less power the U.S. will have to set global standards for how the technology should be used, industry analysts say. That opens the door for Beijing to use Chinese models as a Trojan horse for disseminating information that reflects its preferred view of the world, some warn.... The U.S. also risks losing insight into China's ambitions and AI innovations, according to Ritwik Gupta, AI policy fellow at the University of California, Berkeley. "If they are dependent on the global ecosystem, then we can govern it," said Gupta. "If not, China is going to do what it is going to do, and we won't have visibility." The article also warns of other potential issues: "Further down the line, a breakdown in U.S.-China cooperation on safety and security could cripple the world's capacity to fight future military and societal threats from unrestrained AI." "The fracturing of global AI is already costing Western makers of computer chips and other hardware billions in lost sales... Adoption of Chinese models globally could also mean lost market share and earnings for AI-related U.S. firms such as Google and Meta."

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New Linux Security Flaw Uses Initramfs to Inject Malware  OMG! Ubuntu

New Linux Security Flaw Can Bypass Disk Encryption  OMG! Ubuntu

New Linux Security Flaw Can Bypass Disk Encryption  OMG! Ubuntu

The Free Software Foundation's services face "ongoing (and increasing) distributed denial of service (DDoS) attacks," senior systems administrator Ian Kelling wrote Wednesday. But "Even though we are under active attack, gnu.org, ftp.gnu.org, and savannah.gnu.org are up with normal response times at the moment, and have been for the majority of this week, largely thanks to hard work from the Savannah hackers Bob, Corwin, and Luke who've helped us, your sysadmins." "We've shielded these sites for almost a full year of intense attacks now, and we'll keep on fighting these attacks for as long as they continue." Our infrastructure has been under attack since August 2024. Large Language Model (LLM) web crawlers have been a significant source of the attacks, and as for the rest, we don't expect to ever know what kind of entity is targeting our sites or why. - In the fall Bulletin, we wrote about the August attack on gnu.org. That attack continues, but we have mitigated it. Judging from the pattern and scope, the goal was likely to take the site down and it was not an LLM crawler. We do not know who or what is behind the attack, but since then, we have had more attacks with even higher severity. - To begin with, GNU Savannah, the FSF's collaborative software development system, was hit by a massive botnet controlling about five million IPs starting in January. As of this writing, the attack is still ongoing, but the botnet's current iteration is mitigated. The goal is likely to build an LLM training dataset. We do not know who or what is behind this. - Furthermore, gnu.org and ftp.gnu.org were targets in a new DDoS attack starting on May 27, 2025. Its goal seems to be to take the site down. It is currently mitigated. It has had several iterations, and each has caused some hours of downtime while we figured out how to defend ourselves against it. Here again, the goal was likely to take our sites down and we do not know who or what is behind this. - In addition, directory.fsf.org, the server behind the Free Software Directory, has been under attack since June 18. This likely is an LLM scraper designed to specifically target Media Wiki sites with a botnet. This attack is very active and now partially mitigated... Even though we are under active attack, gnu.org, ftp.gnu.org, and savannah.gnu.org are up with normal response times at the moment, and have been for the majority of this week, largely thanks to hard work from the Savannah hackers Bob, Corwin, and Luke who've helped us, your sysadmins. We've shielded these sites for almost a full year of intense attacks now, and we'll keep on fighting these attacks for as long as they continue. The full-time FSF tech staff is just two systems administrators, "and we currently lack the funds to hire more tech staff any time soon," Kelling points out. Kelling titled his post "our small team vs millions of bots," suggesting that supporters purchase FSF memberships "to improve our staffing situation... Can you join us in our crucial work to guard user freedom and defy dystopia?" Kelling also points out they're also facing "run-of-the-mill standard crawlers, SEO crawlers, crawlers pretending to be normal users, crawlers pretending to be other crawlers, uptime systems, vulnerability scanners, carrier-grade network address translation, VPNs, and normal browsers hitting our sites..." "Some of the abuse is not unique to us, and it seems that the health of the web has some serious problems right now."

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'There are no plans to drop support for SteamOS': The Finals devs commit to Steam Deck and Linux players despite new kernel-level anti-cheat  PC Gamer